Skin and mucous membrane protection in cancer therapy – this is what characterises Again-Life medical products when it comes to minimising or even preventing side effects of chemo- or radiotherapy. The tried-and-tested and patented active ingredient Adelmidrol is the extraordinary feature of the Again-Life product line, which has now been introduced to pharmacies by Bendalis GmbH, Oberhaching.
The active ingredient Adelmidrol, a palmitoylethanolamide analogue, which was further developed by Italian internist and oncologist Dr. Raffaele Migliaccio specifically for cancer therapy, has already been tested in numerous studies across Europe. The fatty acid molecule, which occurs naturally in body cells, binds to receptors on mast cells, thereby regulating excessive mast cell activity and the increased release of messenger substances.
Particularly in cancer patients, who are exposed to particular stress from chemotherapy or radiation therapy, mast cells in the skin and mucous membranes increase their activity. This releases messenger substances and exposes the mast cells to constant stress, resulting in skin damage and pain. Since the body's own palmitoylethanolamide is broken down very rapidly intracellularly, an imbalance thus occurs during chemotherapy or radiation therapy. This lack of a balanced immune response can be effectively counteracted with Adelmidrol. Therapy-related damage to healthy cells with high division rates, such as skin, hair, blood, and intestinal cells, can thus be kept to a minimum.
The Again-Life medicinal products offered in pharmacies vary in their Adelmidrol concentration and formulation, thus enabling a variety of applications for skin and mucous membrane problems, such as those occurring with cancer therapy. The products are available as skin creams and lotions, as vaginal gel, as bladder catheter gel, as mouthwash or spray, as hair lotion, and as anal cream. Depending on the indication and formulation, Dodecain, thioctic acid and lipoic acid are also used, as well as hyaluronic acid, phytosphingosine or the analgesic capsaicin.